Effective services and products dedicated to various research programs targeting the microtubule cytoskeleton (oncology, etc.)
Introduction
Microtubule cytoskeleton plays several major roles in cells. It is particularly important during mitosis, when microtubule-based bipolar spindle assures chromosome partitioning between daughter cells. Failure to properly segregate chromosomes in mitosis is frequently associated with cancerogenesis and tumour progression.
A Monoclonal antibody that demonstrates significant potential as a research and/or diagnostic tool (virology, cancer research, immune-biology)
Introduction
The ZEBRA transactivator is an Epstein-Barr Virus (EBV) protein transactivator controlling the switch of the viral cycle from a latent to productive phase. The Zebra transactivator acts by binding to the promoters of genes involved in lytic DNA replication and activating their transcription. This protein transactivator demonstrates significant potential within a research environment (virology, cancer research, immune-biology) as well as in diagnostics.
A valuable research tool that demonstrates significant potential with regards to the characterization of proliferating cells that over express eIF3.
Introduction
Antibody from this clone recognizes the RNA recognizing motif (RRM) of subunit g of the eukaryotic Initiation Factor 3 (eIF3) molecule. eIF3 binds specifically to mRNA and some viral RNA genomes, and plays an essential role in the translation initiation process. This antibody shows significant potential with regards to the characterization of proliferating cells that over express eIF3.
Epstein Barr Virus R Transactivator (RTA) Technology
A novel antibody enabling the detection and qualification of the RTA protein, a key factor in the detection of early Epstein Barr Virus.
Introduction
The R Transactivator (RTA) is one of the two main transactivators originating from the Epstein Barr Virus (EBV). It acts in synergy with the Zebra protein in the switch-latency productive cycle. The transactivator demonstrates significant potential as a marker for the early detection of EBV infection. This technology is available to license to organisations working in the field of monoclonal antibody distribution.
Anti Translation Eucaryotic Factor (eIF3b) Antibody
A valuable research tool that demonstrates significant potential with regards to the characterization of proliferating cells that over express eIF3
Antibody from this clone recognizes the RNA recognizing motif (RRM) of subunit b of the eukaryotic Initiation Factor 3 (eIF3) molecule. eIF3 binds specifically to mRNA and some viral RNA genomes and plays an essential role in the translation initiation process. This antibody shows significant potential with regards to the characterization of proliferating cells that over express eIF3.
